Adult Still’s Disease. Literature Review

Abstract

Still’s disease is a systematic pathology of unknown etiology, which main characteristics are: feverish peaks, salmon-colored dermatological lesions, arthritis, odynophagia, hepatosplenomegaly and in certain cases, lymphadenopathy. In some patients, ocular, pulmonary, cardiac, renal and nervous system involvement can be observed. The diagnosis is based on clinical and para-clinical data. These have been grouped together as diagnostic criteria and at least 8 groups have been proposed so far. Currently, the development of new drugs for the treatment of this pathology has been possible thanks to advances in the clarification of the pathophysiology. However, there are no large series of studies that support or reject its use in clinical practice, so the fundamental pillar treatment continues to be corticosteroids, non-steroidal anti-inflammatories and disease-modifying anti-rheumatic drugs.